ScienceDaily: Cell Biology News

Scientists offer first definitive proof of bacteria-feeding behavior in green algae

Thu, 23 May 2013 14:37:37 EDT

Researchers have captured images of green alga consuming bacteria, offering a glimpse at how early organisms dating back more than 1 billion years may have acquired free-living photosynthetic cells. This acquisition is thought to be a critical first step in the evolution of photosynthetic algae and land plants, which, in turn, contributed to the increase in oxygen levels in Earth's atmosphere and ocean and provided one of the conditions necessary for animal evolution.

Cinnamon compound has potential ability to prevent Alzheimer's

Thu, 23 May 2013 14:37:37 EDT

Cinnamon: Can the red-brown spice with the unmistakable fragrance and variety of uses offer an important benefit? The common baking spice might hold the key to delaying the onset of -- or warding off -- the effects of Alzheimer's disease.

Biophysicists measure mechanism that determines fate of living cells

Thu, 23 May 2013 14:37:37 EDT

For the first time, biophysicists have measured the molecular force required to mechanically transmit function-regulating signals within a cell. A new laboratory method, named the tension gauge tether approach, has made it possible to detect and measure the mechanics of the single-molecule interaction by which human cell receptors are activated.

New target to boost plant resistance to insects and pathogens identified

Thu, 23 May 2013 14:33:33 EDT

Plants have evolved unique and sophisticated immune systems to defend themselves against insects and pathogens. Plant hormones called jasmonates play an important role in this defense, but jasmonates have been found to also be important for plant growth. Now, researchers have discovered a gene in the jasmonate pathway that controls plant defenses but does not play a detectable role in plant development. These findings could be applied to improve crop resistance in agriculture.

White tiger mystery solved: Coat color produced by single change in pigment gene

Thu, 23 May 2013 14:33:33 EDT

White tigers today are only seen in zoos, but they belong in nature, say researchers reporting new evidence about what makes those tigers white. Their spectacular white coats are produced by a single change in a known pigment gene, according to a new study.

Chemists find new compounds to curb staph infection

Thu, 23 May 2013 09:33:33 EDT

In an age when microbial pathogens are growing increasingly resistant to the conventional antibiotics used to tamp down infection, scientists have synthesized a potent new class of compounds capable of curbing the bacteria that cause staph infections.

Biochemistry: Unspooling DNA from nucleosomal disks

Thu, 23 May 2013 08:30:30 EDT

The tight wrapping of genomic DNA around nucleosomes in the cell nucleus makes it unavailable for gene expression. This study describes a mechanism that allows chromosomal DNA to be locally displaced from nucleosomes for transcription.

Boosting body's natural flu killers as way to offset virus mutation problem

Thu, 23 May 2013 08:30:30 EDT

The known difficulty in fighting influenza (flu) is the ability of the flu viruses to mutate and thus evade various medications that were previously found to be effective. Researchers at the Hebrew University of Jerusalem have shown recently that another, more promising, approach is to focus on improving drugs that boost the body’s natural flu killer system.

Scientists develop worm EEG to test the effects of drugs

Wed, 22 May 2013 18:01:01 EDT

Scientists have developed a device which records the brain activity of worms to help test the effects of drugs. NeuroChip is a microfluidic electrophysiological device, which can trap the microscopic worm Caenorhadbitis elegans and record the activity of discrete neural circuits in its 'brain' - a worm equivalent of the EEG.

Fast new, one-step genetic engineering technology

Wed, 22 May 2013 13:12:12 EDT

A new, streamlined approach to genetic engineering drastically reduces the time and effort needed to insert new genes into bacteria, the workhorses of biotechnology, scientists are reporting. The method paves the way for more rapid development of designer microbes for drug development, environmental cleanup and other activities.

Slowing the aging process -- only with antibiotics

Wed, 22 May 2013 13:11:11 EDT

Scientists reveal the mechanism responsible for aging hidden deep within mitochondria -- and dramatically slow it down in worms by administering antibiotics to the young.

Norway spruce genome sequenced: Largest ever to be mapped

Wed, 22 May 2013 13:10:10 EDT

Scientists have mapped the gene sequence of Norway spruce (the Christmas tree) -- a species with huge economic and ecological importance -- and that is the largest genome to have ever been mapped. The genome is complex and seven times larger than that of humans.

How immune system peacefully co-exists with 'good' bacteria

Wed, 22 May 2013 13:09:09 EDT

The human gut is loaded with helpful bacteria microbes, yet the immune system seemingly turns a blind eye. Now, researchers know how this friendly truce is kept intact. Innate lymphoid cells directly limit the response by inflammatory T cells to commensal bacteria in the gut of mice. Loss of this ILC function effectively puts the immune system on an extended war footing against the commensal bacteria a condition observed in multiple chronic inflammatory diseases.

Eyes on the prey: Researchers analyse the hunting behaviour of fish larvae in virtual reality

Wed, 22 May 2013 11:20:20 EDT

Moving objects attract greater attention -- a fact exploited by video screens in public spaces and animated advertising banners on the Internet. For most animal species, moving objects also play a major role in the processing of sensory impressions in the brain, as they often signal the presence of a welcome prey or an imminent threat. Scientists have now investigated how the brain uses the information from the visual system for the execution of quicker movements.

DNA damage: The dark side of respiration

Wed, 22 May 2013 08:53:53 EDT

Adventitious changes in cellular DNA can endanger the whole organism, as they may lead to life-threatening illnesses like cancer. Researchers now report how byproducts of respiration cause mispairing of subunits in the double helix.

Mechanism discovered which aids Legionella to camouflage itself in the organism

Wed, 22 May 2013 08:52:52 EDT

The feared Legionella pneumophilabacteria is responsible for legionellosis, an infectious disease that can lead to pneumonia. In order to infect us, this pathogen has developed a complex method enabling it to camouflage itself and go unnoticed in our cells, thus avoiding these acting against the infectious bacteria.

Minus environment, patterns still emerge: Computational study tracks E. coli cells' regulatory mechanisms

Tue, 21 May 2013 19:41:41 EDT

Random mutations and genetic drift, rather than design principles, may explain the emergence of regulatory network properties in E. coli.

Bacterium uses natural 'thermometer' to trigger diarrheal disease, scientists find

Tue, 21 May 2013 19:40:40 EDT

How does the bacterium Shigella -- the cause of a deadly diarrheal disease -- detect that it's in a human host? Scientists have found that a biological "RNA thermometer" monitors whether the environment is right for the bacterium to produce the factors it needs to survive within the body, according to a new study.

Single-cell transfection tool enables added control for biological studies

Tue, 21 May 2013 13:22:22 EDT

Researchers have developed a novel tool for single-cell transfection, in which they deliver molecules into targeted cells through temporary nanopores in the cell membrane created by a localized electric field.

Scientists uncover how grapefruits provide a secret weapon in medical drug delivery

Tue, 21 May 2013 13:22:22 EDT

Researchers have uncovered how to create nanoparticles using natural lipids derived from grapefruit, and have discovered how to use them as drug delivery vehicles.

Small but speedy: Short plants live in the evolutionary fast lane

Tue, 21 May 2013 12:14:14 EDT

Biologists have known for a long time that some creatures evolve more quickly than others. Exactly why isn't well understood, particularly for plants. But it may be that height plays a role. Shorter plants have faster-changing genomes.

Vitamin C can kill drug-resistant TB, researchers find

Tue, 21 May 2013 12:12:12 EDT

In a striking, unexpected discovery, researchers have determined that vitamin C kills drug-resistant tuberculosis (TB) bacteria in laboratory culture. The finding suggests that vitamin C added to existing TB drugs could shorten TB therapy, and it highlights a new area for drug design.

'Whodunnit' of Irish potato famine solved

Tue, 21 May 2013 01:12:12 EDT

An international team of scientists reveals that a unique strain of potato blight they call HERB-1 triggered the Irish potato famine of the mid-19th century.

Resistance to last-line antibiotic makes bacteria resistant to immune system

Tue, 21 May 2013 01:12:12 EDT

Bacteria resistant to the antibiotic colistin are also commonly resistant to antimicrobial substances made by the human body, according to a new study. Cross-resistance to colistin and host antimicrobials LL-37 and lysozyme, which help defend the body against bacterial attack, could mean that patients with life-threatening multi-drug resistant infections are also saddled with a crippled immune response.

Parasitic wasps use calcium pump to block fruit fly immunity

Mon, 20 May 2013 16:37:37 EDT

Parasitic wasps switch off the immune systems of fruit flies by draining calcium from the flies' blood cells, a finding that offers new insight into how pathogens break through a host's defenses. Researchers say their findings have uncovered an important component of cellular immunity, one that parasites have learned to take advantage of.

Do salamanders' immune systems hold the key to regeneration?

Mon, 20 May 2013 16:37:37 EDT

Salamanders' immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have found. In new research, scientists have found that when immune cells known as macrophages were systemically removed, salamanders lost their ability to regenerate a limb and instead formed scar tissue.

Compound in Mediterranean diet makes cancer cells 'mortal'

Mon, 20 May 2013 15:43:43 EDT

New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells' "superpower" to escape death.

Fastest measurements ever made of ion channel proteins

Mon, 20 May 2013 15:42:42 EDT

Engineers have used miniaturized electronics to measure the activity of individual ion-channel proteins with temporal resolution as fine as one microsecond, producing the fastest recordings of single ion channels ever performed. They designed a custom integrated circuit to perform these measurements, in which an artificial cell membrane and ion channel are attached directly to the surface of the amplifier chip.

Advance in nanotech gene sequencing technique

Mon, 20 May 2013 13:37:37 EDT

The allure of personalized medicine has made new, more efficient ways of sequencing genes a top research priority. One promising technique involves reading DNA bases using changes in electrical current as they are threaded through a nanoscopic hole. Now, physicists has used solid-state nanopores to differentiate single-stranded DNA molecules containing sequences of a single repeating base.

Making ice-cream more nutritious with meat left-overs

Mon, 20 May 2013 09:48:48 EDT

Most of the animal proteins found in the meat industry waste have, until now, been underutilized. The challenge is to transform such waste into food of higher functionality and added value.

Bacteria use hydrogen, carbon dioxide to produce electricity

Sun, 19 May 2013 19:11:11 EDT

Researchers have engineered a strain of electricity-producing bacteria that can grow using hydrogen gas as its sole electron donor and carbon dioxide as its sole source of carbon.

Computational tool translates complex data into simplified two-dimensional images

Sun, 19 May 2013 14:56:56 EDT

Researchers have developed a computational method that enables scientists to visualize and interpret "high-dimensional" data produced by single-cell measurement technologies such as mass cytometry. The method has particular relevance to cancer research and therapeutics.

Origins of life: In early Earth, iron helped RNA catalyze electron transfer

Sun, 19 May 2013 14:56:56 EDT

A new study shows how complex biochemical transformations may have been possible under conditions that existed when life began on the early Earth. The study shows that RNA is capable of catalyzing electron transfer under conditions similar to those of the early Earth.

Ginger compounds may be effective in treating asthma symptoms, study suggests

Sun, 19 May 2013 14:56:56 EDT

Gourmands and foodies everywhere have long recognized ginger as a great way to add a little peppery zing to both sweet and savory dishes; now, a study shows purified components of the spicy root also may have properties that help asthma patients breathe more easily.

Now we know why old scizophrenia medicine works on antibiotics-resistant bacteria

Sat, 18 May 2013 15:37:37 EDT

An old medicine for schizophrenia is effective at treating something completely different than it was designed for: antibiotic-resistant bacteria. So far it has been a mystery how this old schizophrenia medicine works, but now researchers have figured it out. This can lead to a new medicine against the increasingly threatening antibiotic-resistant bacteria.

Genome sequence of Tibetan antelope sheds new light on high-altitude adaptation

Fri, 17 May 2013 10:27:27 EDT

How can the Tibetan antelope live at elevations of 4,000-5,000m on the Qinghai-Tibetan Plateau? Investigators now provide evidence of genetic factors that may be associated with the species' adaption to harsh highland environments.

New era of fisheries policy needed to secure nutrition for millions

Fri, 17 May 2013 10:26:26 EDT

A new study argues that for fisheries policies to be effective they must take in to account not just fish stock conservation and environmental issues, but also research data on the patterns and dynamics of fish trade, markets and user consumption.

Physicist's tool has potential for brain mapping

Thu, 16 May 2013 16:17:17 EDT

Physicists are developing a new tool that uses low-energy near-infrared light and fiber optics for optogenetic stimulation of cells. He believes it will be a useful tool for mapping physical and functional connections in the brain.

Asian lady beetles use biological weapons against their European relatives

Thu, 16 May 2013 14:25:25 EDT

Once introduced for biological pest control, Asian lady beetle populations have been increasing uncontrollably. Scientists have now found the reason for the animal's success. Its body fluid contains microsporidia, fungus-like protozoa that parasitize body cells and can cause immense harm to their host. The Asian lady beetle is obviously resistant to these parasites. However, transferred to native species, microsporidia can be lethal.

Scientific insurgents say 'Journal Impact Factors' distort science

Thu, 16 May 2013 14:25:25 EDT

An ad hoc coalition of unlikely insurgents -- scientists, journal editors and publishers, scholarly societies, and research funders across many scientific disciplines -- today posted an international declaration calling on the world scientific community to eliminate the role of the journal impact factor in evaluating research for funding, hiring, promotion, or institutional effectiveness.

X-ray tomography of living frog embryo

Thu, 16 May 2013 10:52:52 EDT

Classical X-ray radiographs provide information about internal, absorptive structures of organisms such as bones. Alternatively, X-rays can also image soft tissues throughout early embryonic development of vertebrates. Related to this, a new X-ray method allowed researchers to view three dimensional reconstructions showing developing embryos of the African clawed frog.

Developmental genetics of space and time

Wed, 15 May 2013 16:39:39 EDT

Scientists have conducted a study that reveals important and useful insights into how and why developmental genes often take inputs from two independent “morphogen concentration gradients.”

Squishy hydrogels may be the ticket for studying biological effects of nanoparticles

Wed, 15 May 2013 12:51:51 EDT

A class of water-loving, jelly-like materials with uses ranges ranging from the mundane, such as superabsorbent diaper liners, to the sophisticated, such as soft contact lenses, could be tapped for a new line of serious work: testing the biological effects of nanoparticles, according to scientists.

No idle chatter: Malaria parasites 'talk' to each other

Wed, 15 May 2013 12:50:50 EDT

Scientists have made the surprise discovery that malaria parasites can 'talk' to each other -- a social behavior to ensure the parasite's survival and improve its chances of being transmitted to other humans. The finding could provide a niche for developing antimalarial drugs and vaccines that prevent or treat the disease by cutting these communication networks.

Cotton offers a new ecologically friendly way to clean up oil spills

Wed, 15 May 2013 11:38:38 EDT

With the Deepwater Horizon disaster emphasizing the need for better ways of cleaning up oil spills, scientists are reporting that unprocessed, raw cotton may be an ideal, ecologically friendly answer, with an amazing ability to sop up oil.

Intestinal bacterium Akkermansia curbs obesity

Wed, 15 May 2013 11:37:37 EDT

A dominant and useful bacterium called Akkermansia muciniphila is present in the intestinal system of all humans, from babies to the elderly. This microorganism is found in the intestinal mucus layer that protects against intruders. Even more remarkable is that this bacterium has a favorable effect on the disrupted metabolism associated with obesity.

Untangling the tree of life

Wed, 15 May 2013 09:48:48 EDT

Phylogeneticists examined the reasons why large-scale tree-of-life studies are producing contradictory results and have proposed a suite of novel techniques to resolve the conflicts.

Cells must use their brakes moderately for effective speed control

Wed, 15 May 2013 08:53:53 EDT

How cells regulate their own function by “accelerating and braking” is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy. Scientists now show a model of how cells’ regulatory systems work.

Study IDs key protein for cell death

Tue, 14 May 2013 19:06:06 EDT

Findings may offer a new way to kill cancer cells by forcing them into an alternative programmed-death pathway.

Same musicians play a brand new tune: Unusual interplay of signaling pathways shapes critical eye structure

Tue, 14 May 2013 13:54:54 EDT

A small ensemble of musicians can produce an infinite number of melodies, harmonies and rhythms. So too, do a handful of workhorse signaling pathways that interact to construct multiple structures that comprise the vertebrate body. In fact, crosstalk between two of those pathways -- those governed by proteins known as Notch and BMP (for Bone Morphogenetic Protein) receptors -- occurs over and over in processes as diverse as forming a tooth, sculpting a heart valve and building a brain.

Engineered biomaterial could improve success of medical implants

Tue, 14 May 2013 12:28:28 EDT

Expensive, state-of-the-art medical devices and surgeries often are thwarted by the body's natural response to attack something in the tissue that appears foreign. Now, engineers have demonstrated in mice a way to prevent this sort of response.

Mining the botulinum genome

Tue, 14 May 2013 12:27:27 EDT

Scientists have been mining the genome of C. botulinum to uncover new information about the toxin genes that produce the potent toxin behind botulism.

Cutting-edge bacteria research leads to more effective treatment of complex infections

Tue, 14 May 2013 11:32:32 EDT

Bacteria play a huge role when inflammations attack our body. Now researchers have succeeded in revealing one of the devastating effects of bacteria, and thus it will be possible for the pharmaceutical industry to treat even very complicated bacterial infections.

Alligator stem cell study gives clues to tooth regeneration

Tue, 14 May 2013 10:14:14 EDT

Alligators may help scientists learn how to stimulate tooth regeneration in people, according to new research. For the first time, a global team of researchers has uncovered unique cellular and molecular mechanisms behind tooth renewal in American alligators.

Fish oil may stall effects of junk food on brain

Tue, 14 May 2013 10:14:14 EDT

Data from more than 180 research papers suggests fish oils could minimize the effects that junk food can have on the brain, a review has shown.

Flower power fights orchard pests

Tue, 14 May 2013 10:14:14 EDT

Researchers have found they can control one of fruit growers' more severe pests, aphids, with a remarkably benign tool: flowers. The discovery is a boon for organic as well as conventional tree fruit growers. The researchers found that plantings of sweet alyssum attracted a host of spiders and predator bugs that in turn preyed on woolly apple aphids, a pest that growers often control with chemical sprays.

Microbes capture, store, and release nitrogen to feed reef-building coral

Tue, 14 May 2013 08:54:54 EDT

Microscopic algae that live within reef-forming corals scoop up available nitrogen, store the excess in crystal form, and slowly feed it to the coral as needed, according to a study published in mBio.

Corals turn to algae for stored food when times get tough

Tue, 14 May 2013 08:54:54 EDT

Researchers present new evidence for the crucial role of algae in the survival of their coral hosts. Ultra-high resolution images reveal that the algae temporarily store nutrients as crystals, building up reserves for when supplies run low.

Water governs cell movement: Aquaporins play key role, new research finds

Tue, 14 May 2013 08:53:53 EDT

Water gives life. Researchers now show how the cells in our bodies are driven mainly by water power -- a discovery that in the long run opens the way for a new strategy in cancer therapy.

Most complete database to date of human phosphatases and their substrates

Tue, 14 May 2013 08:53:53 EDT

It is now easier to pinpoint exactly what molecules a phosphatase -- a type of protein that’s essential for cells to react to their environment -- acts upon in human cells, thanks to the free online database DEPOD, created by EMBL scientists. Published today in Science Signaling, the overview of interactions could even help explain unforeseen side-effects of drugs.